PROTEOMICS
Complete Protein Characterization
Comprehensive analysis of protein identity, structure, purity, and stability for research and biopharma.
Capabilities: Structure analysis (primary–quaternary), molecular weight, PTMs, purity, and orthogonal structural confirmation.
Primary structure
High-resolution analysis to confirm amino acid sequence integrity and identify modifications.
Capabilities: Peptide fingerprinting and
Post-translational modifications analysis
Secondary structure
Assessment of protein folding patterns to understand conformational stability, functional behavior, and formulation performance.
Capabilities: CD spectroscopy, FTIR, thermal transition monitoring, and structural comparison across formulations.
Tertiary Structure
Evaluation of three-dimensional protein folding and conformational stability.
Capabilities: CD, fluorescence spectroscopy, NMR, intrinsic/extrinsic fluorescence mapping.
Quaternary structure
Characterization of protein assemblies, interactions, and oligomerization states.
Capabilities: Nano-DSF, SAXS, aggregation & oligomerization profiling, higher-order structure confirmation.
Folding unfolding study
Analysis of structural transitions under stress to predict stability and guide formulation optimization.
Capabilities: Nano-DSC, Nano-DSF, thermal denaturation, refolding efficiency.
Genomic
Whole Genome Sequencing
Complete genomic analysis to provide accurate insights into an organism’s genetic makeup for research, diagnostics, and precision medicine.
Bioinformatics Service
Transforming raw sequencing data into actionable insights across genomics, transcriptomics, proteomics, and clinical datasets.
Process Development
Upstream Process Development
Upstream processing involves the early stages of bioprocess development, beginning with cell line selection, seed train preparation, and controlled cultivation. The goal is to optimize cell growth and maximize expression of the desired biomolecule. This includes establishing ideal culture conditions, such as media composition, nutrient balance, feeding strategies, and bioreactor parameters. Through systematic optimization, upstream development ensures robust, scalable, and reproducible production performance that supports downstream purification and overall process reliability.
Downstream Process Development
Downstream processing focuses on the extraction, purification, and refinement of the target biomolecule after cultivation. Once the product is released into the supernatant or retained within the cells, it undergoes a series of steps designed to remove impurities while preserving biological activity. Typical downstream operations include cell separation, filtration, chromatography, concentration, and polishing. Each step is optimized to enhance product purity, yield, and stability. By fine‑tuning these purification strategies, downstream development ensures that the final product meets stringent quality, safety, and regulatory requirements.